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In patients treated with various doses of losartan and hydrochlorothiazide, there was also a dose-related decrease in the hypokalemic response to hydrochlorothiazide as the dose of losartan was increased, as well as a dose-related decrease in serum uric acid with increasing doses of losartan.
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Gould L, Reddy CV, Zen B, Singh BK "Life-threatening reaction to thiazides.
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SOURCE: Mayo Clinic, news release, Aug.
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